Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 9/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.59 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 6/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19383009 | 0.91 | PHF8 (0.58) | PHF8KDM4CKDM2AKDM5AKDM2B | |
| SCHEMBL17604572 | 0.88 | PHF8 (0.60) | PHF8KDM4CKDM2AKDM5AKDM2B | |
| SCHEMBL24244253 | 0.83 | PHF8 (0.64) | PHF8KDM4CKDM2AKDM5AKDM2B | |
| SCHEMBL17604520 | 0.81 | PHF8 (0.62) | PHF8KDM4CKDM2AKDM5AKDM2B | |
| SCHEMBL16033817 | 0.79 | PHF8 (0.60) | PHF8KDM4CKDM2AKDM5AKDM2B | |
| SCHEMBL17604569 | 0.79 | PHF8 (0.58) | PHF8KDM4CKDM2AKDM5AKDM2B | |
| SCHEMBL17604562 | 0.77 | PHF8 (0.60) | PHF8KDM4CKDM2AKDM5AKDM2B | |
| SCHEMBL19383295 | 0.76 | PHF8 (0.56) | PHF8KDM4CKDM2AKDM5AKDM2B | |
| SCHEMBL19383151 | 0.75 | KDM4C (0.55) | PHF8KDM4CKDM2AKDM5AKDM2B | |
| SCHEMBL17604566 | 0.75 | KDM4C (0.70) | PHF8KDM4CKDM2AKDM5AKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044342-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |