Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 2/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19245380 | 0.84 | MEN1 (0.36) | ALDH1A1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL16121814 | 0.82 | CARM1 (0.42) | ALDH1A1MEN1KMT2AMAPK1KDM4E | |
| SCHEMBL18901285 | 0.79 | KMT2A (0.37) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL3375523 | 0.66 | — | — | |
| SCHEMBL18756770 | 0.66 | — | — | |
| SCHEMBL14823458 | 0.66 | — | — | |
| SCHEMBL22216373 | 0.66 | ALDH1A1 (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2011616 | 0.65 | AKT2 (0.47) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL16201146 | 0.64 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL17950128 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136699-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | EPIZYME, INC (US) | 2017-08-10 | — | — | WO | disclosed |
| WO-2016044556-A2 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |