Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.45 |
| ▸ | HSP90B1 | P14625 | 8/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19505307 | 0.84 | HSP90AA1 (0.43) | HSP90AA1HSP90B1 | |
| SCHEMBL19505305 | 0.81 | HSP90AA1 (0.42) | HSP90AA1HSP90B1 | |
| SCHEMBL19498161 | 0.81 | HSP90AA1 (0.42) | HSP90AA1HSP90B1 | |
| SCHEMBL12840038 | 0.81 | HSP90AA1 (0.40) | HSP90AA1HSP90B1 | |
| SCHEMBL12840947 | 0.76 | HSP90AA1 (0.39) | HSP90AA1HSP90B1 | |
| SCHEMBL12840807 | 0.74 | HSP90AA1 (0.36) | HSP90AA1HSP90B1 | |
| SCHEMBL17623871 | 0.74 | HSP90AA1 (0.45) | HSP90AA1HSP90B1 | |
| SCHEMBL10280068 | 0.71 | HSP90AA1 (0.43) | HSP90AA1HSP90B1 | |
| SCHEMBL17624119 | 0.70 | HSP90AA1 (0.40) | HSP90AA1 | |
| SCHEMBL17623870 | 0.70 | HSP90AA1 (0.48) | HSP90AA1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305922-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-10-26 | — | — | US | disclosed |
| WO-2016044604-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305922-A1 | CARM1 INHIBITORS AND USES THEREOF | CARM1, ADRM1, PRMT1 | HSP90AA1 1748/4885HSP90B1 783/4885LRRK2 444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.