Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 11/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17624089 | 1.00 | BCHE (0.48) | BCHEALDH1A1MAPTCHRM2MEN1 | |
| SCHEMBL17624088 | 1.00 | BCHE (0.48) | BCHEALDH1A1MAPTCHRM2MEN1 | |
| SCHEMBL17623700 | 1.00 | BCHE (0.48) | BCHEALDH1A1MAPTCHRM2MEN1 | |
| SCHEMBL7276665 | 0.90 | BCHE (0.54) | BCHEALDH1A1MAPTCHRM2MEN1 | |
| SCHEMBL12199932 | 0.90 | BCHE (0.54) | BCHEALDH1A1MAPTCHRM2MEN1 | |
| SCHEMBL7150802 | 0.90 | BCHE (0.54) | BCHEALDH1A1MAPTCHRM2MEN1 | |
| SCHEMBL7152562 | 0.90 | BCHE (0.54) | BCHEALDH1A1MAPTCHRM2MEN1 | |
| SCHEMBL16309274 | 0.90 | BCHE (0.47) | BCHEALDH1A1MAPT | |
| SCHEMBL16309279 | 0.90 | BCHE (0.47) | BCHEALDH1A1MAPT | |
| SCHEMBL17618218 | 0.90 | BCHE (0.47) | BCHEALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160326185-A1 | SYNTHESIS OF ISOHEXIDE DICARBAMATES AND DERIVATIVES THEREOF | ARCHER DANIELS MIDLAND COMPANY | 2016-11-10 | — | — | US | disclosed |
| US-9422304-B2 | Synthesis of isohexide dicarbamates and derivatives thereof | ARCHER DANIELS MIDLAND COMPANY (US) | 2016-08-23 | — | — | US | disclosed |
| US-20160083396-A1 | SYNTHESIS OF ISOHEXIDE DICARBAMATES AND DERIVATIVES THEREOF | ARCHER DANIELS MIDLAND CO (US) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083396-A1 | SYNTHESIS OF ISOHEXIDE DICARBAMATES AND DERIVATIVES THEREOF | PRKCA, PRKCE, PRKCI | BCHE 1011/4885ALDH1A1 3338/4885MAPT 1146/4885 |
| US-20160326185-A1 | SYNTHESIS OF ISOHEXIDE DICARBAMATES AND DERIVATIVES THEREOF | PRKCA, PRKCE, PRKCI | BCHE 1011/4885ALDH1A1 3338/4885MAPT 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.