Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | RRM1 | P23921 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26478805 | 0.98 | USP2 (0.58) | USP2DPP7TSHRCA1CA2 | |
| SCHEMBL9676595 | 0.98 | USP2 (0.58) | USP2DPP7TSHRCA1CA2 | |
| SCHEMBL23140154 | 0.94 | USP2 (0.61) | USP2DPP7TSHRCA1CA2 | |
| SCHEMBL22414705 | 0.92 | USP2 (0.69) | USP2DPP7TSHRCA1CA2 | |
| SCHEMBL24072868 | 0.92 | DPP7 (0.61) | USP2DPP7TSHRRRM1EPHX1 | |
| SCHEMBL13609211 | 0.88 | USP2 (0.68) | USP2DPP7TSHRRRM1EPHX1 | |
| SCHEMBL26133522 | 0.87 | GNAI3 (0.57) | USP2DPP7RRM1EPHX1GNAI3 | |
| SCHEMBL5491789 | 0.86 | USP2 (0.71) | USP2DPP7TSHRCA1CA2 | |
| SCHEMBL12769547 | 0.86 | TSHR (0.64) | USP2DPP7TSHRCA1CA2 | |
| SCHEMBL25405485 | 0.86 | HDAC7 (0.56) | USP2DPP7TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044585-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |