Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 12/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524049 | 0.92 | BCL2 (0.75) | BCL2 | |
| SCHEMBL17627311 | 0.91 | BCL2 (0.64) | BCL2 | |
| SCHEMBL17627321 | 0.89 | BCL2 (0.82) | BCL2 | |
| SCHEMBL1956292 | 0.89 | BCL2 (0.91) | BCL2 | |
| SCHEMBL1957560 | 0.88 | BCL2 (1.00) | BCL2 | |
| SCHEMBL30313804 | 0.87 | BCL2 (0.91) | BCL2 | |
| SCHEMBL523310 | 0.87 | BCL2 (0.91) | BCL2 | |
| SCHEMBL1957813 | 0.87 | BCL2 (0.81) | BCL2 | |
| SCHEMBL1958977 | 0.86 | BCL2 (0.75) | BCL2 | |
| SCHEMBL1955360 | 0.85 | BCL2 (0.73) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575463-B1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBVIE INC (US) | 2016-03-30 | — | — | EP | claimed |