Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 14/20 | 0.64 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17627306 | 0.91 | BCL2 (0.78) | BCL2 | |
| SCHEMBL524049 | 0.83 | BCL2 (0.75) | BCL2 | |
| SCHEMBL21291488 | 0.81 | BCL2 (0.72) | BCL2BCL2L1 | |
| SCHEMBL17627321 | 0.79 | BCL2 (0.82) | BCL2BCL2L1 | |
| SCHEMBL1956292 | 0.79 | BCL2 (0.91) | BCL2 | |
| SCHEMBL19940459 | 0.79 | BCL2 (0.63) | BCL2BCL2L1 | |
| SCHEMBL1957560 | 0.78 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1955671 | 0.78 | BCL2 (0.83) | BCL2 | |
| SCHEMBL30313804 | 0.78 | BCL2 (0.91) | BCL2BCL2L1 | |
| SCHEMBL523310 | 0.78 | BCL2 (0.91) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575463-B1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBVIE INC (US) | 2016-03-30 | — | — | EP | claimed |