SCHEMBL17628686

SCHEMBL17628686

Cc1ncccc1N[Si](C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NMT1 P30419 1/20 0.41
P2RX7 Q99572 1/20 0.39
SLC40A1 Q9NP59 10/20 0.38
KMT2A Q03164 5/20 0.38
TDP1 Q9NUW8 4/20 0.38
HTT P42858 3/20 0.38
S1PR4 O95977 2/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
S1PR1 P21453 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
AGTR1 P30556 2/20 0.38
MITF O75030 1/20 0.38
MAPT P10636 1/20 0.38
OPRK1 P41145 1/20 0.38
CKS1B P61024 1/20 0.38
SKP2 Q13309 1/20 0.38
ALOX15 P16050 2/20 0.37
GLO1 Q04760 2/20 0.37
MEN1 O00255 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145899 0.79 KMT2A (0.43) NMT1P2RX7SLC40A1KMT2ATDP1
SCHEMBL5839756 0.78 KDM4E (0.37) KMT2AHTTALDH1A1LMNAMAPT
SCHEMBL15227141 0.77 KMT2A (0.41) NMT1P2RX7SLC40A1KMT2ATDP1
SCHEMBL4143510 0.77 KMT2A (0.41) NMT1P2RX7SLC40A1KMT2ATDP1
SCHEMBL30855342 0.77 KMT2A (0.41) NMT1P2RX7SLC40A1KMT2ATDP1
SCHEMBL883520 0.77
SCHEMBL15231803 0.76
SCHEMBL850058 0.76
SCHEMBL5337824 0.76
SCHEMBL8670176 0.74 HTT (0.50) NMT1P2RX7KMT2AHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478414-B2 Method for hydrophobization of surface of silicon-containing film by ALD ASM IP HOLDING B.V. (NL) 2016-10-25 US disclosed
US-20160093485-A1 Method for Hydrophobization of Surface of Silicon-Containing Film by ALD ASM IP HOLDING B.V. (NL) 2016-03-31 US disclosed