SCHEMBL145899

SCHEMBL145899

Cc1ncccc1Nc1cccnc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
MAPK10 P53779 2/20 0.43
GFER P55789 1/20 0.43
P2RX7 Q99572 1/20 0.42
PTGS2 P35354 1/20 0.41
NMT1 P30419 1/20 0.41
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
HTT P42858 2/20 0.40
KDM4E B2RXH2 2/20 0.40
USP2 O75604 1/20 0.40
POLB P06746 1/20 0.40
ALOX15 P16050 1/20 0.40
GLO1 Q04760 1/20 0.40
NPC1 O15118 2/20 0.39
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
HSP90AA1 P07900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30855342 0.98 KMT2A (0.41) KMT2AMEN1MAPK10GFERP2RX7
SCHEMBL4143510 0.98 KMT2A (0.41) KMT2AMEN1MAPK10GFERP2RX7
SCHEMBL15227141 0.98 KMT2A (0.41) KMT2AMEN1MAPK10GFERP2RX7
SCHEMBL28734979 0.89 MAPK10 (0.51) KMT2AMEN1MAPK10PTGS2MAPT
Alcohol SCHEMBL4977550 0.89 P2RX7 (0.44) KMT2AMEN1MAPK10GFERP2RX7
Acetic Acid SCHEMBL19585268 0.88 P2RX7 (0.47) KMT2AMEN1P2RX7PTGS2ALDH1A1
SCHEMBL10868031 0.86 HTT (0.44) KMT2AMEN1ALDH1A1MAPTHTT
SCHEMBL29581676 0.86 MAPT (0.50) KMT2AMEN1MAPK10ALDH1A1MAPT
SCHEMBL8263591 0.85 GAA (0.47) KMT2AMEN1MAPK10GFERPTGS2
SCHEMBL5771649 0.83 MAPK10 (0.70) KMT2AMEN1MAPK10GFERALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 847 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4732029-A1 METHODS FOR MAGNETIC RESONANCE MOLECULAR IMAGING OF NANOCONSTRUCTS AND USES THEREOF Regents of the University of Michigan (US) 2026-04-29 EP claimed
EP-4263861-B1 COLORIMERIC METHOD FOR DETECTION OF AMPLIFIED GENETIC MATERIAL AND USES THEREOF UNIV NOVA DE LISBOA (PT) 2026-04-08 EP claimed
US-20260035766-A1 PROCESS AND SYSTEM FOR RECOVERING COPPER AND COBALT FROM SULFIDIC MATERIALS CAPSTONE COPPER CORP D/B/A CAPSTONE COPPER (CA) 2026-02-05 US claimed
US-12473250-B2 Molecular design of new antibiotics and antibiotic adjuvants against MCR strains SINGAPORE HEALTH SERVICES PTE LTD (SG) 2025-11-18 US claimed
US-20250296078-A1 TREATING WASTE STREAMS WITH ADVANCED SEPARATION TECHNOLOGIES NEW MATTOCK RESOURCES, INC. (US) 2025-09-25 US claimed
EP-4566669-A2 MOLECULAR DESIGN OF NEW ANTIBIOTICS AND ANTIBIOTIC ADJUVANTS AGAINST MCR STRAINS Singapore Health Services Pte. Ltd. (SG) 2025-06-11 EP claimed
US-20250183399-A1 Processes And Systems For Purifying Independent Streams Of Manganese, Nickel, And Cobalt From Lithium-Ion Battery Waste Streams GREEN LI-ION PTE. LTD. (SG) 2025-06-05 US claimed
WO-2025080353-A1 A PHOSPHATIDYLSERINE TARGETING COMBINATION FOR CANCER IMMUNOTHERAPY PURDUE RESEARCH FOUNDATION (US) 2025-04-17 WO claimed
WO-2025070261-A1 METHOD FOR ANALYZING FOOD COMPONENT BY SELF-ASSEMBLED CHEMOSENSOR 国立大学法人 東京大学 2025-04-03 WO claimed
WO-2025042332-A1 PROCESSES AND SYSTEMS FOR PURIFYING INDEPENDENT STREAMS OF MANGANESE, NICKEL, AND COBALT FROM LITHIUM-ION BATTERY WASTE STREAMS GREEN LI-ION PTE. LTD. (SG) 2025-02-27 WO claimed
EP-0948655-A1 RECOVERY OF NICKEL FROM BIOLEACH SOLUTION BHP MINERALS INTERNATIONAL INC. (US) 1999-10-13 EP claimed
WO-1998026100-A1 RECOVERY OF NICKEL FROM BIOLEACH SOLUTION BHP MINERALS INTERNATIONAL INC. (US) 1998-06-18 WO claimed
US-5626648-A LATERITE ORE OR SULFIDIC ORE BHP MINERALS INTERNATIONAL INC. (US) 1997-05-06 US claimed
WO-1996020291-A1 RECOVERY OF NICKEL AND COBALT FROM LATERITE ORES BHP MINERALS INTERNATIONAL INC. (US) 1996-07-04 WO claimed
US-5178746-A Contacting with ion exchange resin containing picolylamine group BIO-RECOVERY SYSTEMS, INC. (US) 1993-01-12 US claimed
US-5102640-A Demetallization by complexing with silicate particles having ligands on their surfaces SCHLAPFER CARL W (CH) 1992-04-07 US claimed
US-4666683-A WATER INSOLUBLE ION EXCHANGE RESIN ECO-TEC LIMITED (CA) 1987-05-19 US claimed
US-4246350-A MADE FROM STYRENE-DIVINYLBENZENE COPOLYMER WITH REOCCURING UNITS OF BIS-PICOLYLAMINE, IMINO DIACETATE AND HYDROXYETHYL PICOLYLAMINE THE DOW CHEMICAL COMPANY (US) 1981-01-20 US claimed
US-4153605-A Process for preparing bispicolylamine THE DOW CHEMICAL COMPANY (US) 1979-05-08 US claimed
US-4080338-A REACTING CYANOPYRIDINE WITH HYDROGEN, PALLADIUM CATALYST THE DOW CHEMICAL COMPANY (US) 1978-03-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12473250-B2 Molecular design of new antibiotics and antibiotic adjuvants against MCR strains TLR5, TLR6, TLR4 KMT2A 2701/4885MEN1 1668/4885MAPK10 498/4885
US-20260035766-A1 PROCESS AND SYSTEM FOR RECOVERING COPPER AND COBALT FROM SULFIDIC MATERIALS SOD1, XDH, FECH KMT2A 3105/4885MEN1 4563/4885MAPK10 610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.