Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 15/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631972 | 0.88 | GRM5 (0.51) | GRM5 | |
| SCHEMBL17631779 | 0.85 | GRM5 (0.44) | GRM5CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL17631750 | 0.83 | GRM5 (0.38) | GRM5 | |
| SCHEMBL17631978 | 0.83 | GRM5 (0.41) | GRM5ALDH1A1SMN1; SMN2PDE4B | |
| SCHEMBL17632318 | 0.82 | GRM5 (0.41) | GRM5 | |
| SCHEMBL17632045 | 0.80 | ALDH1A1 (0.47) | GRM5L3MBTL1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL17632042 | 0.80 | ALDH1A1 (0.47) | GRM5L3MBTL1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL17632462 | 0.80 | FASN (0.35) | GRM5 | |
| SCHEMBL17632206 | 0.80 | GRM5 (0.36) | GRM5 | |
| SCHEMBL17632538 | 0.79 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |