SCHEMBL17633729

SCHEMBL17633729

CCCCCCC=C[Si](OCCC)(OCCC)OCCC

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.42
TRPV1 Q8NER1 1/20 0.42
LPAR3 Q9UBY5 2/20 0.41
LPAR1 Q92633 1/20 0.41
LPAR2 Q9HBW0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28508445 1.00 FAAH (0.42) FAAHTRPV1LPAR3LPAR1LPAR2
SCHEMBL28513578 1.00 FAAH (0.42) FAAHTRPV1LPAR3LPAR1LPAR2
SCHEMBL17633728 1.00 FAAH (0.42) FAAHTRPV1LPAR3LPAR1LPAR2
SCHEMBL28483996 1.00 FAAH (0.42) FAAHTRPV1LPAR3LPAR1LPAR2
SCHEMBL17633707 0.98 LPAR3 (0.39) FAAHTRPV1LPAR3LPAR1LPAR2
SCHEMBL17633708 0.98 LPAR3 (0.39) FAAHTRPV1LPAR3LPAR1LPAR2
SCHEMBL3483880 0.92 LPAR2 (0.44) FAAHTRPV1LPAR3LPAR1LPAR2
SCHEMBL19282882 0.92 LPAR2 (0.44) FAAHTRPV1LPAR3LPAR1LPAR2
SCHEMBL17633674 0.92 LPAR2 (0.44) FAAHTRPV1LPAR3LPAR1LPAR2
SCHEMBL4630432 0.92 LPAR2 (0.44) FAAHTRPV1LPAR3LPAR1LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11028256-B2 Silica-containing rubber compositions containing specified coupling agents and related methods BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2021-06-08 US disclosed
US-20200123349-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2020-04-23 US disclosed
CN-106062044-B Polysiloxane copolymer, and antistatic agent and resin composition containing same 信越化学工业株式会社 2019-11-26 CN disclosed
US-20170247532-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2017-08-31 US disclosed
EP-3197950-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS Bridgestone Americas Tire Operations, LLC (US) 2017-08-02 EP disclosed
CN-106062044-A Polysiloxane copolymer, and antistatic agent and resin composition containing same 信越化学工业株式会社 2016-10-26 CN disclosed
WO-2016048935-A1 SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2016-03-31 WO disclosed