Cinnamic Acid

Cinnamic Acid

SCHEMBL17633997

O=C(/C=C/c1ccccc1)OC/C=C/c1ccccc1.O=C(O)/C=C/c1ccccc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.61
HDAC3 O15379 1/20 0.61
TNKS O95271 1/20 0.61
HDAC4 P56524 1/20 0.61
HDAC1 Q13547 1/20 0.61
HDAC7 Q8WUI4 1/20 0.61
HDAC2 Q92769 1/20 0.61
HDAC10 Q969S8 1/20 0.61
HDAC11 Q96DB2 1/20 0.61
HDAC8 Q9BY41 1/20 0.61
TNKS2 Q9H2K2 1/20 0.61
HDAC6 Q9UBN7 1/20 0.61
HDAC9 Q9UKV0 1/20 0.61
HDAC5 Q9UQL6 1/20 0.61
LMNA P02545 2/20 0.59
AKR1B10 O60218 3/20 0.56
AKR1B1 P15121 3/20 0.56
PTGER4 P35408 1/20 0.51
PTGER3 P43115 1/20 0.51
PTGER2 P43116 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinnamic Acid SCHEMBL29405909 1.00 HCAR2 (0.61) HCAR2HDAC3TNKSHDAC4HDAC1
SCHEMBL1532460 0.95 LMNA (0.65) HCAR2HDAC3TNKSHDAC4HDAC1
SCHEMBL14764012 0.95 LMNA (0.65) HCAR2HDAC3TNKSHDAC4HDAC1
SCHEMBL827239 0.95 LMNA (0.65) HCAR2HDAC3TNKSHDAC4HDAC1
SCHEMBL112366 0.95 LMNA (0.65) HCAR2HDAC3TNKSHDAC4HDAC1
SCHEMBL112365 0.95 LMNA (0.65) HCAR2HDAC3TNKSHDAC4HDAC1
SCHEMBL11230453 0.92 HCAR2 (0.56) HCAR2HDAC3TNKSHDAC4HDAC1
SCHEMBL11230448 0.92 HCAR2 (0.56) HCAR2HDAC3TNKSHDAC4HDAC1
Formic Acid SCHEMBL5773163 0.90 LMNA (0.59) HCAR2HDAC3TNKSHDAC4HDAC1
Formic Acid SCHEMBL5773170 0.90 LMNA (0.59) HCAR2HDAC3TNKSHDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3197510-A1 DELIVERY SYSTEMS COMPRISING MALODOR REDUCTION COMPOSITIONS The Procter & Gamble Company (US) 2017-08-02 EP disclosed
EP-3197507-A1 MALODOR REDUCTION COMPOSITIONS The Procter and Gamble Company (US) 2017-08-02 EP disclosed
WO-2016049458-A1 DELIVERY SYSTEMS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO disclosed
WO-2016049389-A1 MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO disclosed