⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14470743 | 0.83 | HSD17B10 (0.37) | — | |
| SCHEMBL16707299 | 0.75 | HSD17B10 (0.33) | — | |
| SCHEMBL17326828 | 0.75 | TSHR (0.46) | — | |
| SCHEMBL10502784 | 0.73 | — | — | |
| SCHEMBL17323051 | 0.73 | MEN1 (0.48) | — | |
| SCHEMBL7668593 | 0.73 | PTGS1 (0.41) | — | |
| SCHEMBL8403794 | 0.73 | — | — | |
| SCHEMBL933056 | 0.73 | — | — | |
| SCHEMBL1499632 | 0.73 | — | — | |
| SCHEMBL10957266 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220195501-A1 | Targeted Sequence Detection by Nanopore Sensing of Synthetic Probes | NOOMA BIO, LLC | 2022-06-23 | — | — | US | disclosed |
| US-20170349940-A1 | Targeted Sequence Detection by Nanopore Sensing of Synthetic Probes | NOOMA BIO, LLC | 2017-12-07 | — | — | US | disclosed |
| EP-3198036-A1 | TARGET SEQUENCE DETECTION BY NANOPORE SENSING OF SYNTHETIC PROBES | Two Pore Guys, Inc. (US) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016049657-A1 | TARGET SEQUENCE DETECTION BY NANOPORE SENSING OF SYNTHETIC PROBES | Two Pore Guys, Inc. (US) | 2016-03-31 | — | — | WO | disclosed |