Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14470743 | 0.81 | HSD17B10 (0.37) | HSD17B10 | |
| SCHEMBL759444 | 0.78 | TRPA1 (0.50) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| 2,2'-Dithiodiethanesulfonic Acid SCHEMBL773704 | 0.75 | PTGS1 (0.45) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL13863427 | 0.75 | LMNA (0.45) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| 2,2'-Dithiodiethanesulfonic Acid SCHEMBL8403166 | 0.73 | PTGS1 (0.43) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| 2,2'-Dithiodiethanesulfonic Acid SCHEMBL7864315 | 0.73 | PTGS1 (0.43) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL15282771 | 0.73 | LMNA (0.43) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| 2,2'-Dithiodiethanesulfonic Acid SCHEMBL836069 | 0.73 | PTGS1 (0.43) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL17634264 | 0.73 | — | — | |
| SCHEMBL751071 | 0.73 | LMNA (0.43) | PTGS1PDE4ALMNASLC6A6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6325490-B1 | Nozzle plate with mixed self-assembled monolayer | EASTMAN KODAK COMPANY | 2001-12-04 | — | — | US | claimed |
| US-9758642-B2 | Rubber mixtures containing silicic acid and sulfur-containing additives | LANXESS DEUTSCHLAND GMBH (DE) | 2017-09-12 | — | — | US | disclosed |
| US-20140142227-A1 | RUBBER MIXTURES CONTAINING SILICIC ACID AND SULFUR-CONTAINING ADDITIVES | LANXESS DEUTSCHLAND GMBH (DE) | 2014-05-22 | — | — | US | disclosed |
| US-20020111369-A1 | Aryl sulfonic acids and derivatives as FSH antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-08-15 | — | — | US | disclosed |
| US-6355633-B1 | CONTRACEPTIVES | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-12 | — | — | US | disclosed |
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111369-A1 | Aryl sulfonic acids and derivatives as FSH antagonists | FSHR, GNRHR, LHCGR | PTGS1 2376/4885PDE4A 4239/4885LMNA 3330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.