Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 4/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL2527192 | 0.91 | TSHR (0.75) | TSHRALDH1A1MAPK1TDP1GAA | |
| SCHEMBL21776911 | 0.91 | TSHR (0.75) | TSHRALDH1A1MAPK1TDP1GAA | |
| Acrylic Acid SCHEMBL9769107 | 0.89 | TSHR (0.67) | TSHRALDH1A1MAPK1TDP1GAA | |
| Methacrylic Acid SCHEMBL29066489 | 0.88 | TSHR (0.64) | TSHRALDH1A1MAPK1TDP1GAA | |
| Methacrylic Acid SCHEMBL25360380 | 0.87 | ALDH1A1 (0.73) | TSHRALDH1A1MAPK1TDP1GAA | |
| Methacrylic Acid SCHEMBL9240421 | 0.87 | ALDH1A1 (0.73) | TSHRALDH1A1MAPK1TDP1GAA | |
| Methacrylic Acid SCHEMBL28187669 | 0.86 | TSHR (0.67) | TSHRALDH1A1MAPK1TDP1GAA | |
| Methacrylic Acid SCHEMBL11337162 | 0.82 | ALDH1A1 (0.64) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Acetic Acid SCHEMBL28296226 | 0.81 | TSHR (0.86) | TSHRALDH1A1MAPK1TDP1GAA | |
| SCHEMBL176446 | 0.80 | TSHR (0.46) | TSHRALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1750127-B1 | Method of affinity separation. | SHISEIDO CO LTD (JP) | 2011-07-20 | — | — | EP | disclosed |
| EP-1750127-A1 | AFFINITY PARTICLE AND METHOD OF AFFINITY SEPARATION | Shiseido Company, Limited (JP) | 2007-02-07 | — | — | EP | disclosed |