Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14521931 | 0.81 | ALDH1A1 (0.39) | TDP1ALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL10010823 | 0.81 | ALDH1A1 (0.39) | TDP1ALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL12921952 | 0.79 | CYP2D6 (0.39) | TDP1ALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL10012925 | 0.78 | ALDH1A1 (0.41) | TDP1ALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL13537802 | 0.78 | ALDH1A1 (0.36) | TDP1ALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL10012007 | 0.78 | TSHR (0.46) | TDP1TP53ALDH1A1LMNAHSD17B10 | |
| SCHEMBL11441570 | 0.77 | KMT2A (0.33) | TDP1ALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL10009516 | 0.76 | ALDH1A1 (0.40) | TDP1ALDH1A1LMNAHSD17B10KMT2A | |
| SCHEMBL19827629 | 0.75 | TP53 (0.35) | TDP1TP53 | |
| SCHEMBL6711862 | 0.74 | ALDH1A1 (0.40) | TDP1TP53ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296778-B2 | 3′,5′-cyclic phosphate prodrugs for HCV infection | IDENIX PHARMACEUTICALS, INC. (US) | 2016-03-29 | — | — | US | disclosed |
| US-9296778-B2 | 3′,5′-cyclic phosphate prodrugs for HCV infection | IDENIX PHARMACEUTICALS, INC. (US) | 2016-03-29 | — | — | US | disclosed |