Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12686387 | 0.87 | MAPT (0.56) | SMN1; SMN2RXFP1MAPK1TP53ADORA2B | |
| SCHEMBL15396540 | 0.85 | SMN1; SMN2 (0.70) | SMN1; SMN2RXFP1MAPK1TP53NPSR1 | |
| SCHEMBL12260494 | 0.85 | SMN1; SMN2 (0.76) | SMN1; SMN2RXFP1MAPK1TP53NPSR1 | |
| SCHEMBL25293608 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2RXFP1MAPK1TP53NPSR1 | |
| SCHEMBL12686356 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2RXFP1MAPK1TP53NPSR1 | |
| SCHEMBL12260499 | 0.78 | RXFP1 (0.73) | SMN1; SMN2RXFP1MAPK1TP53ADORA2B | |
| SCHEMBL10178027 | 0.78 | SMN1; SMN2 (1.00) | SMN1; SMN2RXFP1MAPK1TP53NPSR1 | |
| SCHEMBL17744968 | 0.77 | RXFP1 (0.75) | SMN1; SMN2RXFP1MAPK1TP53ADORA2B | |
| SCHEMBL10850696 | 0.77 | SMN1; SMN2 (0.82) | SMN1; SMN2RXFP1MAPK1TP53NPSR1 | |
| SCHEMBL12260301 | 0.76 | RXFP1 (0.71) | SMN1; SMN2RXFP1MAPK1TP53ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296691-B2 | Inhibitors of p75 receptor and their uses | HORACIO URI SARAGOVI (CA) | 2016-03-29 | — | — | US | disclosed |