Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13837752 | 1.00 | ALDH1A1 (0.57) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL13836488 | 0.85 | ALDH1A1 (0.73) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL17635418 | 0.85 | ALDH1A1 (0.73) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL13836603 | 0.82 | ALDH1A1 (0.61) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL13837887 | 0.82 | ALDH1A1 (0.61) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL13829420 | 0.82 | ALDH1A1 (0.44) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL13829392 | 0.82 | ALDH1A1 (0.44) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL5857357 | 0.81 | ALDH1A1 (0.76) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL13836666 | 0.80 | ALDH1A1 (0.56) | ALDH1A1ABCG2KDM4ECYP3A4HPGD | |
| SCHEMBL17635421 | 0.80 | ALDH1A1 (0.56) | ALDH1A1ABCG2KDM4ECYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296717-B2 | Synthesis of C-3 coupled biflavonoids and C-3 coupled biflavonoid analogues | UNIVERSITY OF THE FREE STATE (ZA) | 2016-03-29 | — | — | US | disclosed |