Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CRYZ | Q08257 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Hydroxycyclophosphamide SCHEMBL406857 | 0.83 | NPSR1 (0.54) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| 4-Hydroxycyclophosphamide SCHEMBL17737224 | 0.83 | NPSR1 (0.54) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| SCHEMBL10412573 | 0.79 | NPSR1 (0.42) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| SCHEMBL17899474 | 0.78 | NPSR1 (0.57) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| Perfosfamide SCHEMBL4652 | 0.78 | NPSR1 (0.49) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| Perfosfamide SCHEMBL1650261 | 0.78 | NPSR1 (0.49) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| Perfosfamide SCHEMBL28131626 | 0.76 | NPSR1 (0.48) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| SCHEMBL17897696 | 0.75 | NPSR1 (0.49) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| SCHEMBL12451557 | 0.75 | NPSR1 (0.49) | NPSR1KDM4EALOX15MAPK1CRYZ | |
| SCHEMBL10412920 | 0.75 | NPSR1 (0.53) | NPSR1KDM4EALOX15MAPK1CRYZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336141-B1 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS | THRESHOLD PHARMACEUTICALS INC (US) | 2016-03-30 | — | — | EP | disclosed |