Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 16/20 | 0.40 |
| ▸ | F13A1 | P00488 | 2/20 | 0.40 |
| ▸ | TGM1 | P22735 | 2/20 | 0.40 |
| ▸ | TGM6 | O95932 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046294 | 0.87 | KCNH2 (0.52) | ITGB3ITGA2BTGM2F13A1TGM1 | |
| SCHEMBL1052236 | 0.76 | KCNH2 (0.54) | P2RX7 | |
| SCHEMBL1048233 | 0.74 | KCNH2 (0.55) | KLK7KLK5P2RX7 | |
| SCHEMBL15760198 | 0.73 | KCNH2 (0.56) | P2RX7 | |
| SCHEMBL1051096 | 0.72 | KCNH2 (0.58) | KLK7KLK5P2RX7 | |
| SCHEMBL28290512 | 0.70 | ITGB3 (0.61) | ITGB3ITGA2BTGM2F13A1TGM1 | |
| SCHEMBL28290510 | 0.70 | ITGB3 (0.61) | ITGB3ITGA2BTGM2F13A1TGM1 | |
| SCHEMBL3769436 | 0.70 | KCNH2 (0.60) | — | |
| SCHEMBL15760139 | 0.70 | KCNH2 (0.44) | P2RX7 | |
| SCHEMBL21009799 | 0.69 | ITGB3 (0.62) | ITGB3ITGA2BTGM2F13A1TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2737927-B1 | Imidazo[1,2a]pyrazines and compositions comprising them for the treatment of parasitic diseases | NOVARTIS AG (CH) | 2016-03-30 | — | — | EP | disclosed |