Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | FGF2 | P09038 | 1/20 | 0.34 |
| ▸ | MDK | P21741 | 1/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.34 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.34 |
| ▸ | TACR1 | P25103 | 4/20 | 0.34 |
| ▸ | GJB2 | P29033 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17643426 | 1.00 | NT5E (0.35) | NT5EFGF2MDKSSTR1SSTR2 | |
| SCHEMBL18104451 | 0.97 | NT5E (0.34) | NT5EFGF2MDKSSTR1SSTR2 | |
| SCHEMBL17636515 | 0.94 | FGF2 (0.37) | NT5EFGF2MDKSSTR1SSTR2 | |
| SCHEMBL17636461 | 0.94 | FGF2 (0.37) | NT5EFGF2MDKSSTR1SSTR2 | |
| SCHEMBL19481501 | 0.94 | NT5E (0.33) | NT5EFGF2MDKSSTR1SSTR2 | |
| SCHEMBL17636475 | 0.93 | LGALS8 (0.37) | NT5EFGF2MDKSSTR1SSTR2 | |
| SCHEMBL17636486 | 0.93 | LGALS8 (0.37) | NT5EFGF2MDKSSTR1SSTR2 | |
| SCHEMBL17636468 | 0.92 | FGF2 (0.36) | NT5EFGF2MDKSSTR1SSTR2 | |
| SCHEMBL17643360 | 0.92 | LGALS8 (0.38) | NT5EFGF2MDKSSTR1SSTR2 | |
| SCHEMBL17643237 | 0.92 | LGALS8 (0.38) | NT5EFGF2MDKSSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3000820-A1 | Synthetic vaccines against Streptococcus pneumoniae serotype 8 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-03-30 | — | — | EP | disclosed |