Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17628502 | 0.89 | NR1H2 (0.48) | NR1H2NR1H3MAPTALDH1A1LMNA | |
| SCHEMBL17628507 | 0.87 | NR1H2 (0.51) | NR1H2NR1H3MAPTALDH1A1LMNA | |
| SCHEMBL17628490 | 0.86 | NR1H2 (0.50) | NR1H2NR1H3MAPTALDH1A1LMNA | |
| SCHEMBL28722166 | 0.74 | NR1H2 (0.54) | NR1H2NR1H3MAPTALDH1A1LMNA | |
| SCHEMBL29596169 | 0.73 | POLB (0.60) | NR1H2NR1H3MAPTALDH1A1LMNA | |
| SCHEMBL13325642 | 0.71 | SLC9A1 (0.61) | NR1H2NR1H3MAPTALDH1A1LMNA | |
| SCHEMBL12137363 | 0.71 | MAPT (0.60) | NR1H2NR1H3MAPTALDH1A1LMNA | |
| SCHEMBL12253486 | 0.71 | SLC9A1 (0.56) | NR1H2NR1H3MAPTALDH1A1LMNA | |
| SCHEMBL12253466 | 0.69 | NR1H2 (0.56) | NR1H2NR1H3MAPTALDH1A1LMNA | |
| SCHEMBL29597097 | 0.69 | MAPT (0.50) | NR1H2NR1H3MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732042-B2 | Method for producing pyridazine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |
| US-20160090363-A1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160090363-A1 | METHOD FOR PRODUCING PYRIDAZINE COMPOUND | PLP2, PNPO, CBR3 | NR1H2 2675/4885NR1H3 3737/4885MAPT 2089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.