Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 4/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR5A | P47898 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13245724 | 0.97 | LIMK1 (0.45) | LIMK1ROCK1PIM3TDO2HTR2B | |
| SCHEMBL17640479 | 0.96 | LIMK1 (0.45) | LIMK1ROCK1PIM3TDO2HTR2B | |
| SCHEMBL13245712 | 0.89 | ALOX5 (0.41) | LIMK1ROCK1PIM3TDO2HTR2B | |
| SCHEMBL13245718 | 0.89 | ALOX5 (0.41) | LIMK1ROCK1TDO2HTR2BHTR5A | |
| SCHEMBL11941214 | 0.84 | LIMK1 (0.40) | LIMK1ROCK1PIM3TDO2HTR2B | |
| SCHEMBL20735557 | 0.84 | ALOX5 (0.41) | LIMK1TDO2HTR2BHTR5AIDO1 | |
| SCHEMBL13245702 | 0.83 | LIMK1 (0.34) | LIMK1ROCK1 | |
| SCHEMBL11941210 | 0.83 | LIMK1 (0.38) | LIMK1ROCK1PIM3TDO2HTR2B | |
| SCHEMBL13245701 | 0.82 | KDM4E (0.32) | LIMK1 | |
| SCHEMBL16582800 | 0.81 | ALOX5 (0.42) | LIMK1TDO2HTR2BHTR5AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160093808-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-31 | — | — | US | disclosed |