Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16273559 | 0.92 | SLC6A5 (0.57) | SLC6A5EPHX2F2PRSS1PRSS2 | |
| SCHEMBL16870591 | 0.85 | SLC6A5 (0.59) | SLC6A5EPHX2F2PRSS1PRSS2 | |
| SCHEMBL17636914 | 0.82 | SLC6A5 (0.59) | SLC6A5EPHX2FAAHCNR1CNR2 | |
| SCHEMBL18329855 | 0.78 | SLC6A5 (0.54) | SLC6A5EPHX2F2PRSS1PRSS2 | |
| SCHEMBL16364168 | 0.77 | CYP3A4 (0.54) | SLC6A5EPHX2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL27675779 | 0.76 | EPHX2 (0.60) | SLC6A5EPHX2F2PRSS1PRSS2 | |
| SCHEMBL3057446 | 0.76 | EPHX2 (0.60) | SLC6A5EPHX2F2PRSS1PRSS2 | |
| SCHEMBL29615190 | 0.76 | EPHX2 (0.60) | SLC6A5EPHX2F2PRSS1PRSS2 | |
| SCHEMBL16273558 | 0.75 | SLC6A5 (0.69) | SLC6A5EPHX2CYP3A4CYP2C19FAAH | |
| SCHEMBL23787478 | 0.74 | QPCT (0.53) | SLC6A5EPHX2F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016203337-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | MOHAN M ALAPATI (IN) | 2016-12-22 | — | — | WO | disclosed |
| WO-2016046672-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES AND DIABETES | MOHAN M ALAPATI (IN) | 2016-03-31 | — | — | WO | disclosed |
| WO-2016046675-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISEASES | MOHAN M ALAPATI (IN) | 2016-03-31 | — | — | WO | disclosed |