Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.57 |
| ▸ | CTSS | P25774 | 3/20 | 0.57 |
| ▸ | CTSK | P43235 | 3/20 | 0.57 |
| ▸ | CTSH | P09668 | 1/20 | 0.57 |
| ▸ | KISS1R | Q969F8 | 5/20 | 0.57 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.55 |
| ▸ | DPP3 | Q9NY33 | 2/20 | 0.54 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.53 |
| ▸ | CCKBR | P32239 | 6/20 | 0.53 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.52 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30307184 | 0.93 | CXCR4 (0.56) | CTSLCTSSCTSKCTSHKISS1R | |
| SCHEMBL30608443 | 0.91 | CXCR4 (0.60) | CTSLCTSSCTSKCTSHKISS1R | |
| SCHEMBL29500468 | 0.90 | C5AR1 (0.59) | CTSLCTSSCTSKCTSHKISS1R | |
| SCHEMBL31376716 | 0.90 | CXCR4 (0.55) | CTSLCTSSCTSKCTSHKISS1R | |
| SCHEMBL31506622 | 0.90 | DPP3 (0.61) | CTSLCTSSCTSKCTSHKISS1R | |
| SCHEMBL13144891 | 0.90 | KISS1R (0.58) | CTSLCTSSCTSKCTSHKISS1R | |
| SCHEMBL30597309 | 0.89 | DPP3 (0.57) | CTSLCTSSCTSKCTSHKISS1R | |
| SCHEMBL38652302 | 0.89 | CXCR4 (0.59) | CTSLCTSSCTSKCTSHKISS1R | |
| SCHEMBL31607206 | 0.89 | CXCR4 (0.61) | CTSLCTSSCTSKCTSHKISS1R | |
| SCHEMBL31290071 | 0.89 | CXCR4 (0.61) | CTSLCTSSCTSKCTSHKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046397-A1 | CYCLIC PEPTIDES AGAINST THE OUTER MEMBRANE PROTEIN A (OMPA) FOR THE TREATMENT OF INFECTIONS CAUSED BY GRAM NEGATIVE PATHOGENS | SERVICIO ANDALUZ DE SALUD (ES) | 2016-03-31 | — | — | WO | disclosed |