Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17643138 | 0.86 | KMT2A (0.71) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL21973509 | 0.85 | MAPT (0.54) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL17643136 | 0.84 | MEN1 (0.67) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL17643157 | 0.83 | MEN1 (0.54) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL21973007 | 0.83 | MAPT (0.51) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL17643225 | 0.83 | KMT2A (0.84) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL21658300 | 0.83 | GAA (0.47) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL17643148 | 0.83 | KMT2A (0.74) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL822745 | 0.82 | ESR1 (0.54) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL17643205 | 0.82 | KMT2A (0.82) | MEN1KMT2AGAAMAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016045765-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-03-31 | — | — | WO | disclosed |