Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.44 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14867891 | 0.98 | ESR1 (0.52) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL15446590 | 0.94 | ESR1 (0.52) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL280035 | 0.94 | ESR1 (0.47) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL15446697 | 0.93 | ESR1 (0.48) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL15930564 | 0.92 | ESR1 (0.50) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL16118051 | 0.92 | ESR1 (0.49) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL15394178 | 0.91 | ESR1 (0.53) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL280536 | 0.91 | ESR1 (0.56) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL15446581 | 0.91 | ESR1 (0.47) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL15446503 | 0.90 | ESR1 (0.47) | ESR1ESR2GRIA1CACNG8CACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590967-B1 | USE OF DIBENZOFURANS AND DIBENZOTHIOPHENES SUBSTITUTED BY NITROGEN-BONDED FIVE-MEMBERED HETEROCYCLIC RINGS IN ORGANIC ELECTRONICS | UDC IRELAND LTD (IE) | 2019-05-15 | — | — | EP | disclosed |
| US-9315724-B2 | Metal complexes comprising azabenzimidazole carbene ligands and the use thereof in OLEDs | BASF SE (DE) | 2016-04-19 | — | — | US | disclosed |
| US-9315724-B2 | Metal complexes comprising azabenzimidazole carbene ligands and the use thereof in OLEDs | BASF SE (DE) | 2016-04-19 | — | — | US | disclosed |
| US-9067919-B2 | Use of dibenzofurans and dibenzothiophenes substituted by nitrogen-bonded five-membered heterocyclic rings in organic electronics | BASF SE (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9067919-B2 | Use of dibenzofurans and dibenzothiophenes substituted by nitrogen-bonded five-membered heterocyclic rings in organic electronics | BASF SE (DE) | 2015-06-30 | — | — | US | disclosed |
| US-20120319050-A1 | METAL COMPLEXES COMPRISING AZABENZIMIDAZOLE CARBENE LIGANDS AND THE USE THEREOF IN OLEDS | BASF SE (DE) | 2012-12-20 | — | — | US | disclosed |
| US-20120319050-A1 | METAL COMPLEXES COMPRISING AZABENZIMIDAZOLE CARBENE LIGANDS AND THE USE THEREOF IN OLEDS | BASF SE (DE) | 2012-12-20 | — | — | US | disclosed |
| WO-2012172482-A1 | METAL COMPLEXES COMPRISING AZABENZIMIDAZOLE CARBENE LIGANDS AND THE USE THEREOF IN OLEDS | BASF SE (DE) | 2012-12-20 | — | — | WO | disclosed |
| US-20120007063-A1 | USE OF DIBENZOFURANS AND DIBENZOTHIOPHENES SUBSTITUTED BY NITROGEN-BONDED FIVE-MEMBERED HETEROCYCLIC RINGS IN ORGANIC ELECTRONICS | BASF SE (DE) | 2012-01-12 | — | — | US | disclosed |
| US-20120007063-A1 | USE OF DIBENZOFURANS AND DIBENZOTHIOPHENES SUBSTITUTED BY NITROGEN-BONDED FIVE-MEMBERED HETEROCYCLIC RINGS IN ORGANIC ELECTRONICS | BASF SE (DE) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120319050-A1 | METAL COMPLEXES COMPRISING AZABENZIMIDAZOLE CARBENE LIGANDS AND THE USE THEREOF IN OLEDS | OCIAD1, OCIAD2, OXA1L | ESR1 969/4885ESR2 1439/4885GRIA1 712/4885 |
| US-20120007063-A1 | USE OF DIBENZOFURANS AND DIBENZOTHIOPHENES SUBSTITUTED BY NITROGEN-BONDED FIVE-MEMBERED HETEROCYCLIC RINGS IN ORGANIC ELECTRONICS | DDT, DBF4, POU5F1 | ESR1 2751/4885ESR2 2554/4885GRIA1 2106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.