SCHEMBL17643200

SCHEMBL17643200

O=c1c2cc(-c3ccccc3)ccc2nc(-c2ccc(Br)cc2)n1-c1cccc(-c2ccccc2)c1

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.62
KMT2A Q03164 5/20 0.62
GAA P10253 3/20 0.62
ALDH1A1 P00352 8/20 0.57
LMNA P02545 1/20 0.57
MAPT P10636 3/20 0.54
HSP90AA1 P07900 1/20 0.54
ATM Q13315 1/20 0.54
POLB P06746 1/20 0.49
HTT P42858 1/20 0.47
MDM2 Q00987 1/20 0.46
AVPR1A P37288 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17642998 0.88 MEN1 (0.68) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL21658056 0.88 MEN1 (0.65) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL17643006 0.86 MEN1 (0.59) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL17643003 0.85 MEN1 (0.68) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL17642977 0.83 MEN1 (0.57) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL17643000 0.83 MEN1 (0.60) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL17643205 0.83 KMT2A (0.82) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL17643220 0.82 MEN1 (0.56) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL21972960 0.82 MEN1 (0.61) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL17629396 0.81 MEN1 (0.70) MEN1KMT2AGAAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3197982-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-05-06 EP disclosed
US-10544360-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2020-01-28 US disclosed
WO-2016045765-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-03-31 WO disclosed