Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17643006 | 0.92 | MEN1 (0.59) | MEN1KMT2AATMGAAMAPT | |
| SCHEMBL15810554 | 0.87 | KMT2A (0.56) | MEN1KMT2AATMGAAMAPT | |
| SCHEMBL17643200 | 0.85 | MEN1 (0.62) | MEN1KMT2AATMGAAMAPT | |
| SCHEMBL17642998 | 0.85 | MEN1 (0.68) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL17643007 | 0.84 | MEN1 (0.70) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL17629396 | 0.84 | MEN1 (0.70) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL17642999 | 0.83 | MEN1 (0.66) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL21658056 | 0.83 | MEN1 (0.65) | MEN1KMT2AATMGAAMAPT | |
| SCHEMBL14571460 | 0.82 | KMT2A (0.80) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL9953980 | 0.81 | ATM (0.51) | MEN1KMT2AATMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197982-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-05-06 | — | — | EP | disclosed |
| US-10544360-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016045765-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-03-31 | — | — | WO | disclosed |