Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.54 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176767 | 1.00 | CNR2 (0.54) | CNR2CNR1MAPK1ALDH1A1LMNA | |
| SCHEMBL176628 | 0.92 | MAPK1 (0.45) | CNR2CNR1MAPK1ALDH1A1LMNA | |
| SCHEMBL176606 | 0.92 | MAPK1 (0.45) | CNR2CNR1MAPK1ALDH1A1LMNA | |
| SCHEMBL176620 | 0.91 | CNR2 (0.48) | CNR2CNR1MAPK1ALDH1A1LMNA | |
| SCHEMBL176638 | 0.91 | CNR2 (0.48) | CNR2CNR1MAPK1ALDH1A1LMNA | |
| SCHEMBL176782 | 0.87 | MAPK1 (0.45) | CNR2CNR1MAPK1ALDH1A1LMNA | |
| SCHEMBL300678 | 0.87 | CNR2 (0.48) | CNR2MAPK1PTGER4TRPV4 | |
| SCHEMBL3466374 | 0.85 | CNR2 (0.46) | CNR2CNR1ALDH1A1 | |
| SCHEMBL176823 | 0.85 | CNR2 (0.44) | CNR2CNR1ALDH1A1MEN1KMT2A | |
| SCHEMBL176650 | 0.84 | EPHX2 (0.45) | CNR2CNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | disclosed |