Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5054452 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDMAPTCASP6 | |
| SCHEMBL29581351 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDMAPTCASP6 | |
| SCHEMBL8333925 | 0.81 | ALDH1A1 (0.97) | ALDH1A1KDM4EHPGDMAPTCASP6 | |
| SCHEMBL8333926 | 0.81 | ALDH1A1 (0.97) | ALDH1A1KDM4EHPGDMAPTCASP6 | |
| SCHEMBL29440260 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDMAPTAPOBEC3G | |
| SCHEMBL13736031 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDMAPTAPOBEC3G | |
| SCHEMBL29104759 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMAPTAPOBEC3G | |
| SCHEMBL3513570 | 0.74 | MAPT (0.57) | ALDH1A1KDM4EHPGDMAPTCASP6 | |
| SCHEMBL11921499 | 0.73 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAPTCASP6 | |
| SCHEMBL2164932 | 0.72 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDMAPTHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417102-B1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LTD (GB) | 2016-04-06 | — | — | EP | claimed |
| EP-2417102-B1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LTD (GB) | 2016-04-06 | — | — | EP | disclosed |