Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.58 |
| ▸ | CNR2 | P34972 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17645204 | 0.93 | CNR1 (0.68) | CNR1CNR2CYP2C9GPR55 | |
| SCHEMBL31528996 | 0.93 | CNR1 (0.59) | CNR1CNR2KDM4EMEN1CYP1A2 | |
| SCHEMBL31529047 | 0.92 | CNR1 (0.69) | CNR1CNR2KDM4EMEN1CYP1A2 | |
| SCHEMBL17645293 | 0.92 | CNR1 (0.69) | CNR1CNR2KDM4EMEN1CYP1A2 | |
| SCHEMBL31529005 | 0.92 | CNR1 (0.58) | CNR1CNR2KDM4EMEN1CYP1A2 | |
| SCHEMBL17645307 | 0.91 | CNR1 (0.66) | CNR1CNR2CYP2C9GPR55 | |
| SCHEMBL17645415 | 0.91 | CNR1 (0.59) | CNR1CNR2CYP2C9GPR55 | |
| SCHEMBL31528991 | 0.89 | CNR1 (0.56) | CNR1CNR2KDM4EMEN1CYP1A2 | |
| SCHEMBL31528970 | 0.88 | CNR2 (0.67) | CNR1CNR2KDM4EMEN1CYP1A2 | |
| SCHEMBL31529033 | 0.88 | CNR1 (0.56) | CNR1CNR2KDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10053444-B2 | Cannabinergic nitrate esters and related analogs | UNIVERSITY OF CONNECTICUT (US) | 2018-08-21 | — | — | US | disclosed |
| US-20170001980-A9 | Novel Cannabinergic Nitrate Esters and Related Analogs | UNIVERSITY OF CONNECTICUT | 2017-01-05 | — | — | US | disclosed |
| US-20160096822-A1 | Novel Cannabinergic Nitrate Esters and Related Analogs | MAKRIYANNIS ALEXANDROS (US) | 2016-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10053444-B2 | Cannabinergic nitrate esters and related analogs | CNR2, CNR1, NOS3 | CNR1 2/4885CNR2 1/4885KDM4E 3529/4885 |
| US-20160096822-A1 | Novel Cannabinergic Nitrate Esters and Related Analogs | CNR2, CNR1, CHRNB4 | CNR1 2/4885CNR2 1/4885KDM4E 3809/4885 |
| US-20170001980-A9 | Novel Cannabinergic Nitrate Esters and Related Analogs | CNR2, CNR1, CHRNB4 | CNR1 2/4885CNR2 1/4885KDM4E 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.