SCHEMBL176453

SCHEMBL176453

O=C(O)CCC=CCCC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.64
MAPT P10636 3/20 0.64
CYP19A1 P11511 3/20 0.64
ALDH1A1 P00352 2/20 0.64
RXRA P19793 2/20 0.64
OXER1 Q8TDS5 2/20 0.64
FFAR1 O14842 1/20 0.64
LMNA P02545 3/20 0.53
ALKBH5 Q6P6C2 1/20 0.53
SUCNR1 Q9BXA5 1/20 0.53
EGLN1 Q9GZT9 1/20 0.53
PPARD Q03181 4/20 0.48
PPARA Q07869 4/20 0.48
TERT O14746 3/20 0.48
PTPN1 P18031 3/20 0.48
F7 P08709 3/20 0.48
F3 P13726 3/20 0.48
TOP1 P11387 3/20 0.48
BLM P54132 2/20 0.48
HSD17B10 Q99714 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2540034 1.00 PPARG (0.64) PPARGMAPTCYP19A1ALDH1A1RXRA
SCHEMBL176452 1.00 PPARG (0.64) PPARGMAPTCYP19A1ALDH1A1RXRA
Hydrochloric Acid SCHEMBL10669119 0.97 PPARG (0.61) PPARGMAPTCYP19A1ALDH1A1RXRA
Hydrochloric Acid SCHEMBL955237 0.97 PPARG (0.61) PPARGMAPTCYP19A1ALDH1A1RXRA
SCHEMBL7123184 0.97 PPARG (0.61) PPARGMAPTCYP19A1ALDH1A1RXRA
SCHEMBL7123188 0.97 PPARG (0.61) PPARGMAPTCYP19A1ALDH1A1RXRA
SCHEMBL23191717 0.88 PPARG (0.61) PPARGMAPTCYP19A1ALDH1A1RXRA
SCHEMBL8806631 0.88
SCHEMBL17706747 0.88 ALDH1A1 (0.67) PPARGMAPTCYP19A1ALDH1A1RXRA
SCHEMBL6438019 0.88 ALDH1A1 (0.67) PPARGMAPTCYP19A1ALDH1A1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430498-A (E) Process for preparing oct-4-ene-1, 8-dioic acid 四川科瑞德制药股份有限公司 2024-01-23 CN claimed
CN-117434166-A (E) Method for detecting impurities in-octyl-4-ene-1, 8-diacid 四川科瑞德制药股份有限公司 2024-01-23 CN claimed
CN-117062894-A Coolant with improved temperature stability 巴斯夫欧洲公司 2023-11-14 CN claimed
US-11591452-B2 Emulsifier particles and methods for making and using same INGEVITY SOUTH CAROLINA, LLC (US) 2023-02-28 US claimed
CN-114569726-B Compound for preventing, preventing or treating microbial infection and preparation method and application thereof 太阳雨林(北京)生物医药有限公司 2022-10-28 CN claimed
EP-3805756-A1 SMALL MOLECULE BIOCHEMICAL PROFILING OF INDIVIDUAL SUBJECTS FOR DISEASE DIAGNOSIS AND HEALTH ASSESSMENT Metabolon, Inc. (US) 2021-04-14 EP claimed
CN-106537145-B Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment 麦特博隆股份有限公司 2020-08-25 CN claimed
US-20200148855-A1 EMULSIFIER PARTICLES AND METHODS FOR MAKING AND USING SAME MAINSTREAM PINE PRODUCTS, LLC 2020-05-14 US claimed
US-10597570-B2 Spray dried emulsifier compositions, methods for their preparation, and their use in oil-based drilling fluid compositions INGEVITY SOUTH CAROLINA, LLC (US) 2020-03-24 US claimed
CN-108904530-A A kind of bactericidal nano-silver hemostatic composition 安徽省银锂子生物科技发展有限公司 2018-11-30 CN claimed
WO-2012104183-A1 FUNCTIONALISED NITRILE RUBBERS AND THE PRODUCTION THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2012-08-09 WO claimed
EP-2484700-A1 Functionalised nitrile rubbers and their manufacture LANXESS Deutschland GmbH (DE) 2012-08-08 EP claimed
US-20110206802-A1 BIODEGRADABLE CHEWING GUM BASES AND USES THEREOF FLYNN ALLISON 2011-08-25 US claimed
WO-2010053908-A1 BIODEGRADABLE CHEWING GUM BASES AND USES THEREOF FLYNN ALLISON (US) 2010-05-14 WO claimed
US-6835345-B2 Mixture of thermplastic polyester, rubber, filler and flam retarders DEGUSSA AG (DE) 2004-12-28 US claimed
US-20020180098-A1 Molded object with better short-time deflection temperature under load properties DEGUSSA AG (DE) 2002-12-05 US claimed
EP-1077912-B1 NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES SANOL ARZNEI SCHWARZ GMBH (DE) 2002-07-03 EP claimed
US-5326850-A Radiation crosslinking, high heat deflection temperature BASF AKTIENGESELLSCHAFT (DE) 1994-07-05 US claimed
US-5266656-A Blends of polyamides and polyamides with olefin bonds BASF AKTIENGESELLSCHAFT (DE) 1993-11-30 US claimed
US-4923708-A ARYL, ALKYL OR ALKENYL DICARBOXYLIC ACID, CONFECTIONERY, COATINGS NABISCO BRANDS, INC. (US) 1990-05-08 US claimed