Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17653399 | 0.80 | AAK1 (0.67) | AAK1 | |
| SCHEMBL17653163 | 0.80 | AAK1 (0.67) | AAK1IMPDH2 | |
| SCHEMBL17653204 | 0.79 | AAK1 (0.67) | AAK1 | |
| SCHEMBL17653347 | 0.74 | AAK1 (0.41) | AAK1IMPDH2 | |
| SCHEMBL17493928 | 0.74 | AAK1 (1.00) | AAK1IMPDH2 | |
| SCHEMBL17653170 | 0.73 | AAK1 (0.55) | AAK1IMPDH2 | |
| SCHEMBL17653102 | 0.72 | AAK1 (0.65) | AAK1 | |
| SCHEMBL17653228 | 0.72 | AAK1 (0.67) | AAK1 | |
| SCHEMBL17653221 | 0.71 | AAK1 (0.50) | AAK1 | |
| SCHEMBL17653227 | 0.69 | AAK1 (0.51) | AAK1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3200797-A1 | QUINAZOLINE-BASED KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2017-08-09 | — | — | EP | disclosed |
| WO-2016053794-A1 | QUINAZOLINE-BASED KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-04-07 | — | — | WO | disclosed |