Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | THRB | P10828 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347345 | 0.87 | GAA (0.67) | L3MBTL1GAATP53MAPTTHRB | |
| SCHEMBL4354534 | 0.84 | GAA (0.59) | L3MBTL1GAATP53MAPTTHRB | |
| SCHEMBL4355825 | 0.82 | MAPT (0.60) | L3MBTL1GAATP53MAPTTHRB | |
| SCHEMBL4357648 | 0.81 | MAPT (0.69) | L3MBTL1GAATP53MAPTTHRB | |
| SCHEMBL4348998 | 0.79 | MAPT (0.70) | L3MBTL1GAATP53MAPTTHRB | |
| SCHEMBL17653296 | 0.78 | GAA (1.00) | L3MBTL1GAATP53MAPTTHRB | |
| SCHEMBL1128800 | 0.76 | S1PR5 (0.52) | LMNA | |
| SCHEMBL4359794 | 0.75 | GAA (0.57) | L3MBTL1GAATP53MAPTTHRB | |
| SCHEMBL4345493 | 0.74 | GAA (0.60) | L3MBTL1GAATP53MAPTTHRB | |
| SCHEMBL4347137 | 0.73 | GAA (0.69) | L3MBTL1GAATP53MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10112895-B2 | Antivirals against molluscum contagiosum virus | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-10-30 | — | — | US | claimed |
| EP-3200778-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | The Trustees Of The University Of Pennsylvania (US) | 2017-08-09 | — | — | EP | claimed |
| US-20170217882-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2017-08-03 | — | — | US | claimed |
| WO-2016053893-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-04-07 | — | — | WO | claimed |
| US-10112895-B2 | Antivirals against molluscum contagiosum virus | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-10-30 | — | — | US | disclosed |
| EP-3200778-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | The Trustees Of The University Of Pennsylvania (US) | 2017-08-09 | — | — | EP | disclosed |
| US-20170217882-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2017-08-03 | — | — | US | disclosed |
| US-20170217882-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2017-08-03 | — | — | US | disclosed |
| US-20170217882-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2017-08-03 | — | — | US | disclosed |
| WO-2016053893-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-04-07 | — | — | WO | disclosed |
| WO-2016053893-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10112895-B2 | Antivirals against molluscum contagiosum virus | EIF2AK2, IRF3, ZC3HAV1 | L3MBTL1 2533/4885GAA 67/4885TP53 3463/4885 |
| US-20170217882-A1 | ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS | EIF2AK2, IRF3, ZC3HAV1 | L3MBTL1 2533/4885GAA 67/4885TP53 3463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.