SCHEMBL17653296

SCHEMBL17653296

Oc1ccc(NCc2ccccc2OCc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 1.00
MAPT P10636 7/20 1.00
THRB P10828 6/20 1.00
L3MBTL1 Q9Y468 5/20 1.00
MEN1 O00255 5/20 1.00
BLM P54132 5/20 1.00
KMT2A Q03164 5/20 1.00
TP53 P04637 4/20 1.00
ALDH1A1 P00352 4/20 1.00
KDM4E B2RXH2 3/20 1.00
LMNA P02545 3/20 1.00
TDP1 Q9NUW8 2/20 1.00
HPGD P15428 1/20 1.00
SMN1; SMN2 Q16637 2/20 0.80
POLB P06746 1/20 0.80
ATM Q13315 2/20 0.71
RECQL P46063 1/20 0.71
PLEC Q15149 1/20 0.71
PKM P14618 2/20 0.70
ESR1 P03372 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19194989 0.87 MAPT (0.76) GAAMAPTTHRBL3MBTL1MEN1
SCHEMBL14044002 0.86 MAPT (0.75) GAAMAPTTHRBL3MBTL1MEN1
SCHEMBL4348998 0.83 MAPT (0.70) GAAMAPTTHRBL3MBTL1MEN1
SCHEMBL5778364 0.83 GAA (0.70) GAAMAPTTHRBL3MBTL1MEN1
SCHEMBL4346341 0.83 GAA (0.70) GAAMAPTTHRBL3MBTL1MEN1
SCHEMBL4347137 0.82 GAA (0.69) GAAMAPTTHRBL3MBTL1MEN1
SCHEMBL4357648 0.82 MAPT (0.69) GAAMAPTTHRBL3MBTL1MEN1
SCHEMBL17653420 0.80 MAPT (0.66) GAAMAPTTHRBL3MBTL1MEN1
SCHEMBL4347345 0.80 GAA (0.67) GAAMAPTTHRBL3MBTL1MEN1
SCHEMBL8167324 0.79 LMNA (0.64) GAAMAPTTHRBL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10112895-B2 Antivirals against molluscum contagiosum virus THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2018-10-30 US claimed
EP-3200778-A1 ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS The Trustees Of The University Of Pennsylvania (US) 2017-08-09 EP claimed
US-20170217882-A1 ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2017-08-03 US claimed
WO-2016053893-A1 ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2016-04-07 WO claimed
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES Didenko, Kirill (US) 2025-07-03 US disclosed
CN-120091810-A Methods and highly bioavailable permeable compounds for treating viral diseases 基里尔·迪丹克 2025-06-03 CN disclosed
WO-2023187599-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES DIDENKO KIRILL (MX) 2023-10-05 WO disclosed
US-10112895-B2 Antivirals against molluscum contagiosum virus THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2018-10-30 US disclosed
EP-3200778-A1 ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS The Trustees Of The University Of Pennsylvania (US) 2017-08-09 EP disclosed
US-20170217882-A1 ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2017-08-03 US disclosed
US-20170217882-A1 ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2017-08-03 US disclosed
US-20170217882-A1 ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2017-08-03 US disclosed
WO-2016053893-A1 ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2016-04-07 WO disclosed
WO-2016053893-A1 ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2016-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10112895-B2 Antivirals against molluscum contagiosum virus EIF2AK2, IRF3, ZC3HAV1 GAA 67/4885MAPT 1601/4885THRB 4812/4885
US-20170217882-A1 ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS EIF2AK2, IRF3, ZC3HAV1 GAA 67/4885MAPT 1601/4885THRB 4812/4885
US-20250213601-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES ACE2, FURIN, SARS1 GAA 1541/4885MAPT 330/4885THRB 3882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.