Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23017745 | 1.00 | PSMB5 (1.00) | PSMB5PSMB8 | |
| SCHEMBL28506384 | 0.91 | PSMB5 (1.00) | PSMB5PSMB8 | |
| SCHEMBL17653752 | 0.91 | PSMB5 (1.00) | PSMB5PSMB8 | |
| SCHEMBL15075961 | 0.89 | PSMB5 (0.81) | PSMB5PSMB8 | |
| SCHEMBL17653759 | 0.89 | PSMB5 (1.00) | PSMB5PSMB8 | |
| Hydrochloric Acid SCHEMBL15058246 | 0.89 | PSMB5 (0.79) | PSMB5PSMB8 | |
| SCHEMBL23017770 | 0.89 | PSMB5 (1.00) | PSMB5PSMB8 | |
| Hydrochloric Acid SCHEMBL15058247 | 0.89 | PSMB5 (0.79) | PSMB5PSMB8 | |
| SCHEMBL23017829 | 0.87 | PSMB5 (1.00) | PSMB5PSMB8 | |
| SCHEMBL23665780 | 0.87 | PSMB5 (0.83) | PSMB5PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3201207-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-02-24 | — | — | EP | claimed |
| CN-107001390-B | Boronic acid derivatives | 默克专利股份公司 | 2020-11-27 | — | — | CN | claimed |
| EP-3201207-A1 | BORONIC ACID DERIVATIVES | Merck Patent GmbH (DE) | 2017-08-09 | — | — | EP | claimed |
| WO-2016050359-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2016-04-07 | — | — | WO | claimed |
| EP-3201207-B1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-02-24 | — | — | EP | disclosed |
| US-10294246-B2 | Substituted boronic acids and boronate esters as immunoproteasome inhibitors | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | disclosed |
| US-20180105539-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-04-19 | — | — | US | disclosed |
| US-20180105539-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-04-19 | — | — | US | disclosed |
| EP-3201207-A1 | BORONIC ACID DERIVATIVES | Merck Patent GmbH (DE) | 2017-08-09 | — | — | EP | disclosed |
| WO-2016050359-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2016-04-07 | — | — | WO | disclosed |
| WO-2016050359-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2016-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105539-A1 | BORONIC ACID DERIVATIVES | BCL9, BCL9L, BCL6 | PSMB5 105/4885PSMB8 53/4885 |
| US-10294246-B2 | Substituted boronic acids and boronate esters as immunoproteasome inhibitors | PSMB7, PSMA7, PSMB11 | PSMB5 15/4885PSMB8 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.