Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17655085 | 0.95 | GLS (0.78) | GLS | |
| SCHEMBL17655086 | 0.91 | GLS (0.98) | GLS | |
| SCHEMBL14987305 | 0.90 | GLS (1.00) | GLS | |
| SCHEMBL17655081 | 0.90 | GLS (0.68) | GLS | |
| SCHEMBL14987336 | 0.87 | GLS (1.00) | GLS | |
| SCHEMBL17655252 | 0.85 | GLS (0.65) | GLS | |
| SCHEMBL17193295 | 0.85 | GLS (0.95) | GLS | |
| SCHEMBL15724898 | 0.84 | GLS (0.98) | GLS | |
| SCHEMBL14987335 | 0.83 | GLS (1.00) | GLS | |
| SCHEMBL15724900 | 0.83 | GLS (1.00) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9303002-B2 | Compounds and their methods of use | AGIOS PHARMACEUTICALS, INC. (US) | 2016-04-05 | — | — | US | disclosed |