Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12143361 | 0.94 | APLNR (0.42) | APLNRTDP1ADORA1CA12CA1 | |
| SCHEMBL23818338 | 0.92 | TDP1 (0.43) | APLNRTDP1ADORA1CA12CA1 | |
| SCHEMBL14679532 | 0.89 | APLNR (0.38) | APLNRTDP1ADORA1CA12CA1 | |
| SCHEMBL12028861 | 0.88 | APLNR (0.38) | APLNRTDP1ADORA1CA12CA1 | |
| SCHEMBL15765901 | 0.88 | APLNR (0.38) | APLNRTDP1ADORA1CA12CA1 | |
| SCHEMBL2743022 | 0.87 | TDP1 (0.42) | APLNRTDP1ADORA1CA12CA1 | |
| SCHEMBL13014750 | 0.86 | APLNR (0.37) | APLNRTDP1ADORA1CA12CA1 | |
| SCHEMBL2743023 | 0.86 | APLNR (0.37) | APLNRTDP1ADORA1CA12CA1 | |
| SCHEMBL15757814 | 0.86 | ADORA1 (0.38) | APLNRTDP1ADORA1CA12CA1 | |
| SCHEMBL22339730 | 0.85 | ADORA1 (0.37) | APLNRTDP1ADORA1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828224-B1 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES | AMBRX INC (US) | 2016-04-06 | — | — | EP | disclosed |