Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18462512 | 0.96 | MEN1 (0.51) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL2706749 | 0.96 | MEN1 (0.51) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL204799 | 0.92 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL14982455 | 0.92 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL9977356 | 0.92 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL2707843 | 0.92 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL2757464 | 0.91 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL205797 | 0.91 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL2707839 | 0.91 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL9977354 | 0.89 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-3002281-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2016-04-06 | — | — | EP | disclosed |