Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ESRRB | O95718 | 1/20 | 0.32 |
| ▸ | ESRRA | P11474 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2756468 | 0.88 | LMNA (0.35) | PGRDHODHUSP2ALOX15KDM4E | |
| SCHEMBL14985628 | 0.83 | KDM4E (0.39) | PGRDHODHUSP2ALOX15ALDH1A1 | |
| SCHEMBL9980128 | 0.83 | LMNA (0.35) | PGRDHODHUSP2ALOX15ALDH1A1 | |
| SCHEMBL15463302 | 0.80 | ESRRB (0.36) | PGRESRRBESRRADHODHUSP2 | |
| SCHEMBL2705798 | 0.79 | LMNA (0.35) | PGRESRRBESRRAUSP2ALOX15 | |
| SCHEMBL2756788 | 0.79 | DHODH (0.36) | PGRDHODHUSP2ALOX15ALDH1A1 | |
| SCHEMBL14985621 | 0.78 | ESRRB (0.36) | PGRESRRBESRRADHODHUSP2 | |
| SCHEMBL9980113 | 0.74 | ESR1 (0.35) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL2756786 | 0.74 | ESR1 (0.35) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL10278824 | 0.74 | DHODH (0.41) | PGRDHODHUSP2ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002281-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2016-04-06 | — | — | EP | disclosed |