Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204112 | 0.91 | CA1 (0.55) | HCRTR1HCRTR2CA1CA2CA12 | |
| SCHEMBL16937873 | 0.89 | TDP1 (0.57) | CA1CA2CA12CA7CA9 | |
| SCHEMBL14950619 | 0.86 | TDP1 (0.53) | CA1CA2CA12CA7CA9 | |
| SCHEMBL14950616 | 0.86 | TDP1 (0.53) | CA1CA2CA12CA7CA9 | |
| SCHEMBL204113 | 0.85 | KDM4E (0.53) | HCRTR1HCRTR2CA1CA2CA12 | |
| SCHEMBL28268790 | 0.83 | KDM4E (0.54) | CA1CA2CA12CA7CA9 | |
| SCHEMBL1232173 | 0.82 | TDP1 (0.53) | HCRTR1HCRTR2CA1CA2CA12 | |
| SCHEMBL30010685 | 0.82 | TDP1 (0.53) | HCRTR1HCRTR2CA1CA2CA12 | |
| SCHEMBL1459771 | 0.82 | TDP1 (0.53) | HCRTR1HCRTR2CA1CA2CA12 | |
| SCHEMBL1529069 | 0.82 | NOTUM (0.43) | HCRTR1HCRTR2CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-3002281-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2016-04-06 | — | — | EP | disclosed |