SCHEMBL1765629

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1765662	0.85	NPC1 (0.50)	TSHRMAPTCA1CA2CA12
	SCHEMBL25216751	0.85	CYP4A11 (0.58)	TSHRMAPTCA1CA2CA12
	SCHEMBL1765677	0.84	MGLL (0.50)	TSHRMAPTCA1CA2CA12
	SCHEMBL17023761	0.84	MAPT (0.49)	TSHRMAPTCA1CA2CA12
	SCHEMBL29732761	0.83	MAPT (0.49)	TSHRGAAMAPTCA1CA2
	SCHEMBL11901631	0.83	SLC6A2 (0.51)	TSHRMAPTCA1CA2CA12
	SCHEMBL14661699	0.83	SLC6A2 (0.51)	TSHRMAPTCA1CA2CA12
	SCHEMBL3195273	0.83	CYP4A11 (0.51)	TSHRGAAMAPTCA1CA2
	SCHEMBL1765145	0.83	MAPT (0.49)	TSHRGAAMAPTCA1CA2
	SCHEMBL19922898	0.83	MAPT (0.49)	TSHRGAAMAPTCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.