Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 10/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17656261 | 0.88 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL12104873 | 0.79 | MAPK13 (0.42) | MAPK13MAPK12MAPK11MAPK14PYGL | |
| SCHEMBL19697871 | 0.78 | MAPK13 (0.40) | MAPK13MAPK12MAPK11MAPK14PYGL | |
| SCHEMBL9977462 | 0.78 | MAPK13 (0.37) | MAPK13MAPK12MAPK11MAPK14PYGL | |
| SCHEMBL7600347 | 0.77 | SCN10A (0.43) | MAPK13MAPK12MAPK11MAPK14PYGL | |
| SCHEMBL16891266 | 0.76 | SSTR3 (0.34) | SSTR3KCNH2HPGDSCACNA1FCACNA1D | |
| SCHEMBL12437629 | 0.74 | SSTR3 (0.36) | SSTR3KCNH2HPGDSCACNA1FCACNA1D | |
| SCHEMBL2706498 | 0.73 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14PYGL | |
| SCHEMBL204798 | 0.73 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14PYGL | |
| Hydrochloric Acid SCHEMBL12098609 | 0.72 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-3002281-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2016-04-06 | — | — | EP | disclosed |