Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 14/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17656297 | 0.88 | MAPK13 (0.36) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL12437629 | 0.83 | SSTR3 (0.36) | SSTR3KCNH2CACNA1FCACNA1DCACNA1S | |
| SCHEMBL12436380 | 0.78 | SSTR3 (0.33) | MAPK13MAPK12MAPK11MAPK14SSTR3 | |
| SCHEMBL16891266 | 0.77 | SSTR3 (0.34) | SSTR3KCNH2CACNA1FCACNA1DCACNA1S | |
| SCHEMBL10132664 | 0.76 | MAPK13 (0.53) | MAPK13MAPK12MAPK11MAPK14TRPV1 | |
| SCHEMBL825046 | 0.76 | MAPK13 (0.53) | MAPK13MAPK12MAPK11MAPK14TRPV1 | |
| SCHEMBL456621 | 0.75 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14TRPV1 | |
| SCHEMBL9977194 | 0.75 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14TRPV1 | |
| SCHEMBL16577375 | 0.75 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14TRPV1 | |
| SCHEMBL17014411 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-3002281-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2016-04-06 | — | — | EP | disclosed |