SCHEMBL1765634

SCHEMBL1765634

COC(=O)[C@@H](O)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1765471 1.00
SCHEMBL1765469 1.00
Hydrochloric Acid SCHEMBL2232227 0.97
Hydrochloric Acid SCHEMBL2239793 0.97
Hydrochloric Acid SCHEMBL2232225 0.97
SCHEMBL23792888 0.82 SMN1; SMN2 (0.31)
SCHEMBL1555156 0.80
SCHEMBL7741435 0.80
SCHEMBL1556637 0.80
Hydrochloric Acid SCHEMBL1094574 0.78 GABRR1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025075817-A1 METHODS FOR SYNTHESIS OF PROTEIN HETERO-POLYMERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-04-10 WO disclosed
US-11078202-B2 β-lactamase inhibitor and use thereof Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) 2021-08-03 US disclosed
US-11078202-B2 β-lactamase inhibitor and use thereof Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) 2021-08-03 US disclosed
CN-111670187-B Beta-lactamase inhibitor and use thereof 苏州信诺维医药科技有限公司 2021-04-16 CN disclosed
US-20210046057-A1 Beta-lactamase inhibitor and use thereof Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) 2021-02-18 US disclosed
US-20210046057-A1 Beta-lactamase inhibitor and use thereof Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) 2021-02-18 US disclosed
US-20210032260-A1 Beta-lactamase inhibitor and use thereof Evopoint Biosciences Co., Ltd. (CN) 2021-02-04 US disclosed
US-20210032260-A1 Beta-lactamase inhibitor and use thereof Evopoint Biosciences Co., Ltd. (CN) 2021-02-04 US disclosed
EP-3293184-B1 PYRIMIDINE CARBOXAMIDES AS SODIUM CHANNEL BLOCKERS PURDUE PHARMA LP (US) 2020-12-16 EP disclosed
EP-3744722-A1 ß-LACTAMASE INHIBITOR AND USE THEREOF Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) 2020-12-02 EP disclosed
US-20070249688-A1 Glucagon Receptor Antagonists, Preparation and Therapeutic Uses ELI LILLY AND COMPANY (US) 2007-10-25 US disclosed
EP-1758853-A1 GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES ELI LILLY AND COMPANY (US) 2007-03-07 EP disclosed
WO-2005123668-A1 GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES ELI LILLY AND COMPANY (US) 2005-12-29 WO disclosed
US-6846820-B2 For therapy of diabetes, hyperglycemia, hypercholesterolemia, hypertension, hyperinsulinemias, hyperlipidemia, atherosclerosis and myocardial ischemia in mammals PFIZER INC. (US) 2005-01-25 US disclosed
US-20040006088-A1 For therapy of diabetes, hyperglycemia, hypercholesterolemia, hypertension, hyperinsulinemias, hyperlipidemia, atherosclerosis and myocardial ischemia in mammals PFIZER INC. 2004-01-08 US disclosed
US-6649634-B2 Use in treating diabetes, hyperglycemia, hypercholesterolemia, hypertension, hyperinsulinemias, hyperlipidemia, atherosclerosis and myocardial ischemia in mammals PFIZER, INC. 2003-11-18 US disclosed
US-20020028810-A1 Use in treating diabetes, hyperglycemia, hypercholesterolemia, hypertension, hyperinsulinemias, hyperlipidemia, atherosclerosis and myocardial ischemia in mammals HOOVER DENNIS J (US) 2002-03-07 US disclosed
US-6297269-B1 Substituted n-(indole-2-carbonyl-) amides and derivatives as glycogen phosphorylase inhibitors PFIZER INC. 2001-10-02 US disclosed
EP-0832066-B1 SUBSTITUTED N-(INDOLE-2-CARBONYL-) AMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS PFIZER (US) 2001-09-12 EP disclosed
WO-1996039385-A1 SUBSTITUTED N-(INDOLE-2-CARBONYL-) AMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS PFIZER INC. (US) 1996-12-12 WO disclosed