Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.35 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.35 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13334342 | 0.81 | PDE1A (0.41) | KMT2AL3MBTL1LMNAMTORADRA2A | |
| SCHEMBL9608310 | 0.75 | PDE1B (0.41) | KMT2AL3MBTL1LMNAADRA2AALDH1A1 | |
| SCHEMBL13334360 | 0.73 | LMNA (0.38) | KMT2AL3MBTL1LMNAMTORKCNQ3 | |
| SCHEMBL2455942 | 0.72 | PDE1B (0.48) | ADRA2AP2RX3ALDH1A1KDM4EMAPT | |
| SCHEMBL16378553 | 0.71 | PDE4A (0.38) | KMT2AL3MBTL1LMNAADRA2AP2RX3 | |
| SCHEMBL13334441 | 0.70 | PDE1A (0.41) | ADRA2AP2RX3PDE9APOLBCYP1A2 | |
| SCHEMBL9608344 | 0.67 | MAPT (0.34) | KMT2AL3MBTL1LMNAKCNQ3KCNQ2 | |
| SCHEMBL2460367 | 0.66 | PDE1A (0.45) | KMT2AADRA2AP2RX3ALDH1A1KDM4E | |
| SCHEMBL9608345 | 0.66 | PDE1B (0.35) | L3MBTL1LMNAADRA2AP2RX3MAPT | |
| SCHEMBL9608307 | 0.66 | PDE1B (0.48) | ALDH1A1KDM4EMAPTPDE9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367428-B1 | ORGANIC COMPOUNDS | INTRA CELLULAR THERAPIES INC (US) | 2016-04-06 | — | — | EP | disclosed |