SCHEMBL17656830

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13707581	0.94	ACE2 (0.76)	ACE2ABCG2ABCB1ABCC1PLG
	SCHEMBL14594144	0.90	ACE2 (0.83)	ACE2ABCG2ABCB1ABCC1PLG
	SCHEMBL3173948	0.90	ABCG2 (0.80)	ACE2ABCG2ABCB1ABCC1PLG
	SCHEMBL15689700	0.89	ACE2 (0.74)	ACE2ABCG2ABCB1ABCC1PLG
	SCHEMBL19749974	0.88	ACE2 (0.72)	ACE2ABCG2ABCB1ABCC1PLG
	SCHEMBL17620268	0.86	ACE2 (0.80)	ACE2ABCG2ABCB1ABCC1PLG
	SCHEMBL17656837	0.86	PLG (0.79)	ABCG2ABCB1ABCC1PLGNOX4
	SCHEMBL3181661	0.83	CYP3A4 (0.62)	ACE2ABCG2ABCB1ABCC1PLG
	SCHEMBL15689632	0.83	ABCG2 (0.65)	ACE2ABCG2ABCB1ABCC1PLG
	SCHEMBL29738596	0.83	ABCG2 (0.65)	ACE2ABCG2ABCB1ABCC1PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.