Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.72 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.61 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15689700 | 0.99 | ACE2 (0.74) | ACE2ABCG2ABCB1ABCC1ADORA3 | |
| SCHEMBL29738596 | 0.93 | ABCG2 (0.65) | ACE2ABCG2ABCB1ABCC1ADORA3 | |
| SCHEMBL15689632 | 0.93 | ABCG2 (0.65) | ACE2ABCG2ABCB1ABCC1ADORA3 | |
| SCHEMBL15690698 | 0.92 | ACE2 (0.64) | ACE2ABCG2ABCB1ABCC1ADORA3 | |
| SCHEMBL18176618 | 0.88 | ACE2 (0.61) | ACE2ABCG2ABCB1ABCC1PLG | |
| SCHEMBL17656830 | 0.88 | ACE2 (0.68) | ACE2ABCG2ABCB1ABCC1ADORA3 | |
| SCHEMBL3173948 | 0.88 | ABCG2 (0.80) | ACE2ABCG2ABCB1ABCC1PLG | |
| SCHEMBL17656837 | 0.83 | PLG (0.79) | ABCG2ABCB1ABCC1PLGNOX4 | |
| SCHEMBL18102797 | 0.83 | ACE2 (0.58) | ACE2ABCG2ABCB1ABCC1ADORA3 | |
| SCHEMBL18176615 | 0.82 | TUBB4A (0.57) | ACE2ABCG2ABCB1ABCC1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850221-B2 | Sulfated and unsulfated flavonoid oligomers as cancer therapeutics | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2017-12-26 | — | — | US | disclosed |