Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12462194 | 0.88 | TSHR (0.51) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL13647776 | 0.88 | TSHR (0.68) | TSHRALDH1A1MAPT | |
| SCHEMBL4138562 | 0.88 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1753863 | 0.87 | TSHR (0.56) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL429195 | 0.86 | TSHR (0.49) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL20117523 | 0.84 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1753633 | 0.84 | TSHR (0.53) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL18786168 | 0.84 | TSHR (0.48) | TSHRALDH1A1 | |
| SCHEMBL982002 | 0.82 | TSHR (0.74) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL410380 | 0.82 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724850-B2 | Method of manufacturing an artificial elastic implant for restorative an reconstructive surgery | ICONLAB, USA, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-20160096292-A1 | Method of Manufacturing an Artificial Elastic Implant for Restorative an Reconstructive Surgery | ICONLAB, USA, INC. | 2016-04-07 | — | — | US | disclosed |